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Safety and Effectiveness Research

Proposed human application leads to proven clinical application.

The NEI supports a number of activities to bridge the gap between the proposed human application of a discovery, and new medicines, devices, or surgeries work in people. NEI also collaborates with the Food and Drug Administration (FDA) to facilitate the ophthalmic regulatory approval process.

Age-Related Eye Disease Study (AREDS) logo

The Age-Related Eye Disease Study (AREDS) is a major clinical trial sponsored by the NEI to evaluate the effect of nutritional supplements on the progression of age-related macular degeneration (AMD) and cataract.

Learn more about the Age-Related Eye Disease Study (AREDS)

The NEI uses a number of funding mechanisms to support clinical trials through conception, protocol development, recruitment and retention, treatment and follow-up, and close out. NEI also supports research networks to facilitate clinical trials in specific disease areas, such as pediatric eye disease and diabetic retinopathy.

Explore collaborative clinical research at NEI

Last updated: December 27, 2024