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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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153 items
Eye chart for testing vision

Therapy could improve, prolong sight in those suffering vision loss

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.
Patient undergoes and eye exam. Courtesy National Eye Institute.

For Aging Patients, One Missed Doctor’s Visit Can Lead to Vision Loss

Missing a single ophthalmology appointment over a two-year period was associated with decreased visual acuity for patients with macular degeneration according to a new Penn Medicine study.
Brad Gelfand, Ph.D., in the laboratory

Potential Way to Halt Blinding Macular Degeneration Identified

Researchers at the University of Virginia have successfully treated age-related macular degeneration (AMD) in mice after finding an unexpected link between the two main forms of the blinding eye disease.
Schematic showing how to produce iPS cells

NIH launches first U.S. clinical trial of patient-derived stem cell therapy to replace and repair dying cells in retina

Researchers at the National Eye Institute (NEI) are launching a clinical trial to test the safety of a novel patient-specific stem cell-based therapy to treat geographic atrophy, the advanced “dry” form of age-related macular degeneration.
Image of scanning electron micrograph

NIH, NIST researchers use artificial intelligence for quality control of stem cell-derived tissues

Researchers used artificial intelligence (AI) to evaluate stem cell-derived “patches” of retinal pigment epithelium (RPE) tissue for implanting into the eyes of patients with age-related macular degeneration (AMD), a leading cause of blindness.
Diagram of RPE cell loss

Report: Dry AMD requires broad, systems biology approach leveraging big data, multiple disciplines

A large-scale, collaborative, systems biology approach is needed to expedite the discovery of treatments for dry age-related macular degeneration (AMD) – a leading cause of blindness among people 65 and older for which is there is no treatment.
Grantee News

Experimental Drug Delivers One-Two Punch to Vision Loss

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.
Greens, beans and dairy products arranged on a table

NIH Study Finds No Evidence That Calcium Increases Risk of AMD

Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the findings of a study by scientists at the National Eye Institute (NEI).
Grantee News

With Single Gene Insertion, Blind Mice Regain Sight

Researchers at the University of California, Berkeley, find that restoring opsins with gene therapy can make 'blind' cells light-sensitive; potential human treatment within three years.
Two boys smile at camera. Dark spot in center of image represents vision loss from AMD.

NIH Researchers Home in on Genes Linked to Age-Related Macular Degeneration

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older.