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NEI Research News

Thanks to the work of NEI scientists and grantees, we’re constantly learning new information about the causes and treatment of vision disorders. Get the latest updates about their work — along with other news about NEI.

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Comparison of two retinal images.

Gene therapy for rare eye disease safe but lacks efficacy in early trial

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose.

Noninvasive technique collects sufficient tear fluid to look for biomarkers of health and disease

Scientists from Augusta University have fine-tuned a non-invasive and efficient way to evaluate the tear film for clues about wellness and disease.

Life after death for the human eye

Scientists have revived light-sensing neuron cells in organ donor eyes and restored communication between them as part of a series of discoveries that stand to transform brain and vision research.

Retinal cell map could advance precise therapies for blinding diseases

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists from the National Eye Institute (NEI) discovered five subpopulations of retinal pigment epithelium.

NEI researchers discover cellular events that precede neurodegenerative eye disease

Molecular and cellular changes in rod photoreceptors are detectable in a mouse model of retinal degeneration several days prior to observable morphological changes, according to researchers at the National Eye Institute.
Schematic shows blood vessel leakage on side of retina

Vision improvement is long-lasting with treatment for blinding blood vessel condition

NIH-funded study finds many patients with retinal vein occlusion have vision benefits, but require long-term monitoring and treatment

How do our eyes stay focused on what we reach for? Researchers uncover how our gaze is “anchored” in the brain

Findings offer new insights into how our movements are coordinated

Ultrasound gave us our first baby pictures. Can it also help the blind see?

The research team in the USC Viterbi School of Engineering’s Department of Biomedical Engineering is exploring a non-surgical solution that could restore sight by using another of the five senses. Sound.
Image of Cortical neurons

Scientists unveil the format of working memory

A team of scientists has discovered how working memory is “formatted”—a finding that enhances our understanding of how visual memories are stored.
Cells of fruit fly visual system stained in rainbow colors

Scientists pinpoint what makes brain cells develop in a specific order

A study of the visual system of fruit flies reveals factors regulating neuron development and uncovers similarities with human brain development

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