NEI Research News

People who spend eight or more hours a day staring at a computer screen may notice their eyes becoming tired or dry, and, if those conditions are severe enough, they may eventually develop dry eye disease (DED).

Participants in a phase I/II clinical trial of a new enzyme-based treatment for severe dry eye disease experienced reduced signs of disease and discomfort, according to a paper in Translational Vision Science and Technology.

Mouse, human data suggest inflammation tips immune response, which disrupts oil glands.

Omega-3 fatty acid supplements taken orally proved no better than placebo at relieving symptoms or signs of dry eye, according to the findings of a well-controlled trial funded by the National Eye Institute (NEI), part of the National Institutes of Health

NEI funded researchers at the University of Illinois at Chicago have identified an enzyme present in the cornea that trigger inflammation during–and even after–a herpes virus infection. Their results are published in the journal Cell Reports.

Recent strides toward understanding dry eye are leading to better and longer-lasting therapies for the millions of people in the U.S. who are affected by the condition.

For some people it feels like a speck of sand in the eye, or stinging or burning that doesn’t go away. For others, dry eye disease (or simply dry eye) can become a chronic condition that leads to blurred vision or even vision loss if it goes untreated.