NEI Research News

Diabetes-related vision loss most often is blamed on blood vessel damage in and around the retina, but new research indicates that much of that vision loss may result from nerve cell injury that occurs long before any blood vessels are damaged.

Researchers at the University of Pennsylvania showed that in a form of canine blindness retinal cells continue to differentiate for a period of time early in a dog’s life before overwhelming cell death caused the retina to degenerate.

Making the most of the low light in the muddy rivers where it swims, the elephant nose fish survives by being able to spot predators amongst the muck with a uniquely shaped retina, the part of the eye that captures light.

Researchers at LSU Health New Orleans have shown that a protein critical to the body’s ability to remove waste products from the brain and retina is diminished in age-related macular degeneration.

Andrew Butler may be one of the hardest working people at NIH. He has to be, because he works at the NIH Central Animal Facility—home to the many rodents and other laboratory animals that are a vital part of NIH research.

A two-year clinical trial that compared three drugs for diabetic macular edema (DME) found that gains in vision were greater for participants receiving the drug Eylea (aflibercept) than for those receiving Avastin (bevacizumab).

Researchers from the Harvard Medical School Department of Ophthalmology and the Schepens Eye Research Institute of Mass. Eye and Ear have gained new insight into how a noninflammatory state is maintained in the body.

A new study by at the University of Rochester shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring the connections between nerve cells.

A new study, funded in part by NEI, sheds light on the innate plasticity of the adult brain at its most fundamental level — the synapse.

An NEI-funded researcher at the University of Kentucky College of Medicine discovered with an international team a previously unrecognized function for antibodies.