Promising treatment for disease that destroys eye tissue

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.
The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.
Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

October 9, 2018

Immunology Uveitis

Translational Research

Grantee

Researchers at the University of North Texas Health Science Center have shown that the MDM2 inhibitor class of drugs can treat uveitis in mice.

The disease is caused by inflammatory responses inside the eye, perhaps because of an attack from the body’s immune system. Infections or tumors, bruises and toxins that penetrate the eye might also lead to the disease.