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New UC Irvine-led study shows repeated stress accelerates aging of the eye

November 21, 2022
Aging Genetics Glaucoma Optic Nerve Disorders
Basic Research
Grantee

Dorota Skowronska‐Krawczyk, University of California Irvine, and colleagues showed in a mouse model of glaucoma that fluctuations in eye pressure activate a stress response that is similar to natural aging, as measured by epigenetic changes in retina tissue. Aging is a major risk factor for glaucoma, which is often accompanied by elevated intraocular pressure.

UC Irvine news story