IUPUI researchers re-create retinal microenvironment in a dish with human stem cells

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.
The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.
Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

January 24, 2019

Glaucoma Optic Nerve Disorders Retina Stem Cells

Basic Research

Grantee

IUPUI biologists, growing human pluripotent stem cell-derived retinal ganglion cells in the lab, have developed a way to create more-mature models that better mimic the environment in the human retina. By introducing hPSC-RGCs to astrocytes, researchers can create cells that are more analogous to human RGCs and can be further used to study diseases such as glaucoma.